After reuniting with Gwen Stacy, Miles Morales — Brooklyn's full-time, friendly neighborhood Spider-Man — is catapulted across the Multiverse, where he encounters a team of Spider-People charged with protecting its very existence. But when the heroes clash on how to handle a new threat, Miles finds himself pitted against the other Spiders and must redefine what it means to be a hero so he can save the people he loves most.